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簡(jiǎn)要描述：Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminis
產(chǎn)品型號(hào)：bs-1153R-FITC廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-03-05訪 問 量： 127產(chǎn)品分類
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