亚洲在外线中文字幕_国产毛片一区无码视频精品_国内精品一区二区三区视频_无码国产在线永久不卡_超碰岛国尤物在线观看_一区二区韩国福利网站_国产吃奶摸下激烈视频无遮挡_国产一区二区视频91_狼人亚洲国内精品自在线_日韩AV无码一区二区久久_色吊丝二区三区中文字幕_曰产无码熟妇人妻中文字幕_久爱精品视频热播在线看1_中出到高潮呻吟视频免费体验_亚洲国产Av色精品

歡迎來到北京博奧森生物技術(shù)有限公司網(wǎng)站!
咨詢熱線

4009019800

當(dāng)前位置:首頁  >  新聞資訊  >  11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

更新時(shí)間:2025-01-21  |  點(diǎn)擊率:42

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


截止目前,引用Bioss產(chǎn)品發(fā)表的文獻(xiàn)共32473篇總影響因子159154.82分,發(fā)表在Nature, Science, Cell以及Immunity等頂級(jí)期刊的文獻(xiàn)共122篇,合作單位覆蓋了清華、北大、復(fù)旦、華盛頓大學(xué)、麻省理工學(xué)院、東京大學(xué)以及紐約大學(xué)等國際研究機(jī)構(gòu)上百所。

我們每月收集引用Bioss產(chǎn)品發(fā)表的文獻(xiàn)。若您在當(dāng)月已發(fā)表SCI文章,但未被我公司收集,請致電Bioss,我們將贈(zèng)予現(xiàn)金鼓勵(lì),金額標(biāo)準(zhǔn)請參考“發(fā)文章 領(lǐng)獎(jiǎng)金"活動(dòng)頁面。

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)






本文主要分享引用Bioss 產(chǎn)品發(fā)表文章至 Cell, SCIENCE, Immunity,  Advanced Materials, ACS Nano , Translational Medicine等期刊的 7篇 IF>15的文獻(xiàn)摘要,讓我們一起欣賞吧。



                                   

Cell [IF=45.5]




















11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品

bs-0296P | Mouse IgG Other

作者單位:中國科學(xué)院動(dòng)物研究所

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要:To systematically characterize the loss of tissue integrity and organ dysfunction resulting from aging, we produced an in-depth spatial transcriptomic profile of nine tissues in male mice during aging. We showed that senescence-sensitive spots(SSSs)colocalized with elevated entropy in organizational structure and that the aggregation of immunoglobulin-expressing cells is a characteristic feature of the microenvironment surrounding SSSs. Immunoglobulin G(IgG)accumulated across the aged tissues in both male and female mice, and a similar phenomenon was observed in human tissues, suggesting the potential of the abnormal elevation of immunoglobulins as an evolutionarily conserved feature in aging. Furthermore, we observed that IgG could induce a pro-senescent state in macrophages and microglia, thereby exacerbating tissue aging, and that targeted reduction of IgG mitigated aging across various tissues in male mice. This study provides a high-resolution spatial depiction of aging and indicates the pivotal role of immunoglobulin-associated senescence during the aging process.



                                               

Cell [IF=45.5]


























11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品:

bs-41408P | Recombinant SARS-Cov-2 N protein, N-His | Other

作者單位美國西奈山伊坎醫(yī)學(xué)院
11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要Pathogens constantly evolve and can develop mutations that evade host immunity and treatment. Addressing these escape mechanisms requires targeting evolutionarily conserved vulnerabilities, as mutations in these regions often impose fitness costs. We introduce adaptive multi-epitope targeting with enhanced avidity (AMETA), a modular and mult ivalent nanobody platform that conjugates potent bispecific nanobodies to a human immunoglobulin M(IgM)scaffold. AMETA can display 20+ nanobodies, enabling superior avidity binding to multiple conserved and neutralizing epitopes. By leveraging multi-epitope SARS-CoV-2 nanobodies and structure-guided design, AMETA constructs exponentially enhance antiviral potency, surpassing monomeric nanobodies by over a million-fold. These constructs demonstrate ultrapotent, broad, and durable efficacy against pathogenic sarbecoviruses, including Omicron sublineages, with robust preclinical results. Structural analysis through cryoelectron microscopy and modeling has uncovered multiple antiviral mechanisms within a single construct. At picomolar to nanomolar concentrations, AMETA efficiently induces inter-spike and inter-virus cross-linking, promoting spike post-fusion and striking viral disarmament. AMETA’s modularity enables rapid, cost-effective production and adaptation to evolving pathogens.






                                   

Science [IF=44.7]




















11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品:

bs-0295G-Cy5 | Goat Anti-Rabbit IgG H&L, Cy5 conjugated | IF

bs-0295G-Cy3 | Goat Anti-Rabbit IgG H&L, Cy3 conjugated | IF

作者單位:南方科技大學(xué)

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要:Living with water, cells are frequently challenged by osmotic perturbations. The imbalance between the osmotic pressures across the semipermeable plasma membrane forces water to move in or out of a cell(through a process known as osmosis), remolds its shape, and can have substantial effects on various cellular activities. To preserve appropriate water and to maintain a suitable size, cells must sense and adapt to osmotic changes within their surrounding environments. This is particularly true for most plant cells because they are directly exposed to the fluctuations of environmental osmolarity. For example, the root cells of land plants have to face osmotic stresses generated from dramatic changes of soil moisture, temperature, and salinity, which are major threats to agricultural production. Over the past decades, great efforts have been made to understand the adaptations of plants to such osmotic stresses, although how environmental osmotic changes are sensed by plant cells is far from fully understood.



                                   

Advanced Materials [IF=27.4]




















11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品:

bs-23640R TLR9 Rabbit pAb IF, IHC

作者單位:四川大學(xué)華西醫(yī)院

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要:Orofacial muscles are particularly prone to refractory fibrosis after injury, leading to a negative effect on the patient's quality of life and limited therapeutic options. Gaining insights into innate inflammatory response-fibrogenesis homeostasis can aid in the development of new therapeutic strategies for muscle fibrosis. In this study, the crucial role of macrophages is identified in the regulation of orofacial muscle fibrogenesis after injury. Hypothesizing that orchestrating macrophage polarization and functions will be beneficial for fibrosis treatment, nanomaterials are engineered with polyethylenimine functionalization to regulate the macrophage phenotype by capturing negatively charged cell-free nucleic acids(cfNAs). This cationic nanomaterial reduces macrophage-related inflammation in vitr and demonstrates excellent efficacy in preventing orofacial muscle fibrosis in vivo. Single-cell RNA sequencing reveals that the cationic nanomaterial reduces the proportion of profibrotic Gal3+ macrophages through the cfNA-mediated TLR7/9-NF-κB signaling pathway, resulting in a shift in profibrotic fibro-adipogenic progenitors(FAPs) from the matrix-producing Fabp4+ subcluster to the matrix-degrading Igf1+ subcluster. The study highlights a strategy to target innate inflammatory response-fibrogenesis homeostasis and suggests that cationic nanomaterials can be exploited for treating refractory fibrosis.


                                    

Science Translational

Medicine [IF=15.8]




















11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品:

bs-8621R | PDE3B Rabbit pAb | WB

作者單位:中山大學(xué)附屬第一醫(yī)院

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要:In liver transplantation, donor livers are typically stored in a preservation solution at 4°C for up to 12 hours. However, this short preservation duration can lead to various issues, such as suboptimal donor-recipient matching and limited opportunities for organ sharing. Previous studies have developed a long-term preservation method called supercooling liver preservation(SLP) to address these issues. However, in this study using a rat model, we observed that long-term SLP led to more severe liver damage compared with clinically prevalent traditional static cold storage(SCS) for durations less than 8 hours. To understand the potential mechanism of SLP-induced liver injury, we conducted an integrative metabolomic, transcriptomic, and proteomic analysis. We identified the PDE3B-cAMP-autophagy pathway as a key determinant of SLP-induced liver injury. Specifically, we found that PDE3B was elevated during SLP, which promoted a reduction of cAMP metabolites, triggering an AMPK-dependent autophagy process that led to liver injury in rats. We found that blocking the reduction in cAMP using the PDE3B inhibitor cilostamide inhibited autophagy and substantially ameliorated liver injury during 48-hour SLP in rat livers. Furthermore, we validated the effectiveness of cilostamide treatment in preventing liver injury in pig and human liver 48-hour SLP models. In summary, our results reveal that metabolic reprogramming involving the PDE3B-cAMP-autophagy axis is the key determinant of liver injury in long-term SLP and provide an early therapeutic strategy to prevent liver injury in this setting.



                                   
ACS Nano [IF=15.8]



















11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品:

bs-16644R | H9N2 Hemagglutinin HA1 Rabbit pAb | WB
bs-2001R | H1N1 Hemagglutinin 1 Rabbit pAb | WB

作者單位:北京大學(xué)

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要:The coronavirus disease 2019(COVID 19)pandemic has driven major advances in virus research. The role of glycans in viral infection has been revealed, with research demonstrating that terminal sialic acids are key receptors during viral attachment and infection into host cells. However, there is an urgent demand for universal tools to study the mechanism of sialic acids in viral infections, as well as to develop therapeutic agents against epidemic viruses through the downregulation of terminal sialic acid residues on glycans acting as a glyco-virus checkpoint to accelerate virus clearance. In this study, we developed a robust sialic acids blockade tool termed local and noninvasive glyco-virus checkpoint nanoblockades(LONG NBs), which blocked cell surface sialic acids by endogenously and continuously inhibiting the de novo sialic acids biosynthesis pathway. Furthermore, LONG NBs could accurately characterize the sialic acid-dependent profiles of multiple virus variants and protected the host against partial SARS-CoV-2, rotavirus, and influenza A virus infections after local and noninvasive administration. Our results suggest that LONG NBs represent a promising tool to facilitate in-depth research on the mechanism of viral infection, and serve as a broad-spectrum protectant against existing and emerging viral variants via glyco-virus checkpoint blockade.



                                     

ACS Nano [IF=15.8]




















11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)


文獻(xiàn)引用產(chǎn)品:

bs-6313R | 4 Hydroxynonenal Rabbit pAb | IHC
作者單位:蘇州大學(xué)

11月文獻(xiàn)戰(zhàn)報(bào)Bioss抗體新增高分文獻(xiàn)精彩呈現(xiàn)

摘要:Recent research has highlighted the pivotal role of lipoxygenases in modulating ferroptosis and immune responses by catalyzing the generation of lipid peroxides. However, the limitations associated with protein enzymes, such as poor stability, low bioavailability, and high production costs, have motivated researchers to explore biomimetic materials with lipoxygenase-like activity. Here, we report the discovery of lipoxygenase-like two-dimensional (2D) MoSnanosheets capable of catalyzing lipid peroxidation and inducing ferroptosis. The resulting catalytic products were successfully identified using mass spectrometry and a luminescent substrate. Unlike native lipoxygenases, MoSnanosheets exhibited exceptional catalytic activity at extreme pH, high temperature, high ionic strength, and organic solvent conditions. Structure–activity relationship analysis indicates that sulfur atomic vacancy sites on MoSnanosheets are responsible for their catalytic activity. Furthermore, the lipoxygenase-like activity of MoS2 nanosheets was demonstrated within mammalian cells and animal tissues, inducing distinctive ferroptotic cell death. In summary, this research introduces an alternative to lipoxygenase to regulate lipid peroxidation in cells, offering a promising avenue for ferroptosis induction.





97精品熟女少妇一区| J?P?NESEHD熟女熟妇伦| 欧美精品1区2区3区| 天天激清| 国产不卡免费在线视频| 天天天天操| 亚洲精品人妻在线| 日韩性爱长视频免费| 欧美强奸乱能| A片A5445444| 人人扣人人操| 成年女人黄网站| 亚洲无码偷拍| 五月天婷婷基地| 日日摸夜夜夜夜爽| 高清无码久操视频| 99视频在线| 国产一区二区三区精品观看啪| www.av在线观看| 精品国产丝袜一区二区三区乱码 | 天天看天天在线精品| 超碰在线看| 五月天黄色激情视频| 色欲av一区二区三区蜜芽| 97色在线| 亚洲日韩精品在线播放| 国产麻豆福利av在线播放| 中文字幕美女91| 精品免费视频国产一区| 大香蕉啪啪网| 亚洲成人久久美女| 91强奸乱轮| 亞洲久久直播| 亚洲av综合色区无码一| 国产欧美精选激情视频| a一区二区三区乱码在线| 国产91影院| 久久产精品一区二区三区电影| 亚州AV无码国产精品| 日本免费人成视频播放120秒| 日韩肏逼视频| 日韩欧美亚洲自拍偷拍| 91综合色噜噜| 日本乱人伦片中文三区| 免费岛国一级片| 国产自制av蜜乳| 国产精品一区二区手机看片| yw尤物av无码点击进入麻豆| 国产品精品自在在线午夜免费| 人人爱人人操人人性| 久干9操| 极品美女福利在线观看| 玖玖玖玖精品国产剧情| 亚洲无线码一区国产欧美国| 久久色情| 亚洲AV成人精品网站在AV| 久久av无码| 人人操人人摸人人看人人干| 亚洲欧美在线观看2021| 91一起操| 波多野结衣之双飞调教在线播放 | 91狠狠色丁香婷婷综合久久精品| 国产精品久久久鸭无码的功能| 一区二区三区四区免费视频| 欧美麻豆成人同性GⅤ在线| 久久xx| 中文字幕AV乱伦| 日逼国产| 亚洲av性爱电影| 人妻少妇被猛烈进入中| 最新日韩黄片| 亚洲成人激情小说视频| 精品人体无圣光凹凸| 亚洲欧美国产日本一区二区三区| 五月丁香婷婷综合网| 人妻无一区二区三区| 无码高清专| 超碰成人人人爽人人爽| 亚洲欧美自拍偷拍| 五月天综合在线| 国产视频一区二区三区在线免费观看| av网站国产主播在线| 一级黄色性爱A级片| 99热在线播放| 青娱乐久久艹| 牛牛操视频逼| 丁香婷婷大香蕉| 综合久久久久久久综合网| 99亚洲天堂| 老司机深夜影院18未满| 亚洲网站一区二区在线| 亚洲精品aa久久伊人| 欧美性爱日韩高清| 熟女被操视频网址| xxxx网站亚洲精品| 亚洲影院成人| 久久五月综合| 婷婷视频在线免费观看| 亚洲另类欧美精品| 五月激情在线| 在线观看av区| av在线免费一区二区| 人人操人人爽人人操人人| 成人性爱电影一区二区| 操逼www.| 久久精品福利影院| 国产精品久久久啊| 色噜噜狠狠色综合日日| 草莓精品视频| 日本天天操| 无码国产Av| 日本成人A片网站| 五月丁香黄色网| wwwss在线观看| 久热久| 99热精品在线观看| 91久热| 五月天婷婷影院| A久久| 极品销魂美女一区二区| 九热视频| 99久久婷婷| 99久久婷婷国产综合精品草原| 国产精品无码av在线 | 超碰在线观看av不卡| 中文AV制服乱伦| 日本人妻最新在线中| www.狠狠操| 久久大黄片| 激情六月婷婷| 熟妇综合一区二区三区| 毛片久久| 天天操人人操狠狠插| 一本色道综合久久欧美| 久久透逼视频| 国产精品无码久久久久2028| 日韩精品人妻一| 亚洲国产一级精品毛一级精品看免费视频| 91色人妻| 亚洲色系另类精品国产| 26uuu性物| 操我无码| 婷婷色婷婷| 成人自拍三级在线观看| 性爱免费视频成人| a天堂视频| 再深点灬舒服灬太大了好硬好爽| 中文字幕 国产 精品| 色色亚洲| 国产精品亚洲免费| AV九九| 国产又黄又爽又刺激久久久久久| 天天躁日日躁成人字幕aⅴ| 日本操逼二区| 人人爱操| 免费αⅴ在线观看| 我要看免费韩日黄片| 亚洲免费看片| 亚洲熟女精品| 色狠狠综合| 黄色av网站在线播放| 一区二区三区精品久久| 人人爱人人乐人人操| www.av在线视频| 天天做天天爱天天爽| 青娱乐欧美激情一区二区| 无码国产精品午夜不卡(| 色哟哟综合| 色综合尤物| 最新av网站在线观看| 日韩一级片| 日韩人妻制服丝袜av| 日本天天操| 久久久麻豆精品| 玖玖爱在线视频免费观看| 亚州AV无码国产精品| 久久透逼视频| 99热这里只有精品9| 国产精品无码av嫩草| 亚洲无992tv| 中文字幕av乱伦| 国产特级毛片AAAAAA高潮流水| 久久东京国产精品视频| 午夜福利无毒不卡| 国产操逼网站亚洲一级黄色| 欧美人人AAA| 欧美一区二区三区另类精品| 亚洲精品自拍| 99热久| 日本123区操B视频| 加勒比久久综合网高清| 成人av在线播放| 草草草视频在线免费看| 人人色人人操在线| 亚洲国产麻豆一区二区三区| A 在线网址| 成人小说视频在线精品欧美| 尤物网站91| 天天插天天插| 九九99久久| 日本99视频| 久久五月婷| 亚洲色综合| 99碰碰| 五月丁香综合啪啪| 亚洲高清无码免费观看视频| 精品黑人一区二区| 国产成人bd在线观看| 日韩性爱免费视频在线网站| 日韩欧美国产一区二区三区四区| av毛片aaaaa免费看| 可免费观看的av毛片中日美韩| 婷婷色播婷婷| 久99| 操b在线观看| 亚洲 欧美 制服 另类 自拍| 亚洲色图尤物视频| 精品人妻一区二区视频| 精品久久久久av影院| 333kkkk·亚洲com久久| 果冻国产精品麻豆成人av| 欧美日韩国产色图在线| 久久久精品国产亚洲AV无码| 99热色精品| 亚洲天堂五月天国产| 涩涩这里只有精品视频| jizzjizz欧美| 免費黃色視頻觀看一| 五月婷在线| 无遮挡一级毛片视频免费的| 亚洲最新av无码成人精品区| 人人射人人操人人摸| www.91久久| 成年人黄色视频免费| 老熟女乱子伦中文字幕一区二区| 国产Aα| 女人高潮抽搐喷水视频网站| 久久产精品一区二区三区电影| 视频国产欧美在线播放| 99久久久无码精品国产人| 无码在线亚洲| 大香蕉一级黄色片久久| 香蕉热人人精品| 国产黄色av大片网站| 乱伦熟女论坛| 久久久久久久久成人av解说| 99热啪啪| 一类av片在线看| 97人人超| 午夜激情成人在线观看| 在线99热| 久草国产在线视频| 天天操综合网| 不卡一区二区日本视频| 色婷五月天| 国产真实野战在线视频| 亚洲精品国产精品成人| 激情综合网五月婷婷五月天| 免费在线看黄片av| 亚欧性爱ab| 老外又粗又长一晚做五次| 国产乱伦一二三区| 曰韩操B| 蜜臀一区二区三区在线| 91精品无码人妻系列| 国产一区二区在线播放量| 激情五月天色色| 亚洲国产精品无码AV在线| 视频一区二区免费在线| 人人考人人摸人人干| 乱论91| 一区操逼| 边做饭边操逼逼| 九九热视频在线观看| 欧美东京热精品A∨| 日韩国产不卡在线视频| 国产真乱mangent| 五月丁香大香蕉| av凤凰久久久| av无码精品久久久久| 三级色综合| 日韩乱伦AⅤ| 伊人一区二区在线播放| 999久久久免费精品国产牛牛| 五月天婷精品激情| 男人高清无码一区二区| 免费av在线播放二区| 亚洲婷婷综合网| 最新日本中文字幕| 一级毛片电影免费看| 国产一级高清免费观看| 激情深爱五月天| 亚洲另类在线观看| 亚洲另类在线观看| 另类小说五月天| 麻豆久久精品亚洲精品88| 日本99热| 天天拍天天操| 91肉片| 亚洲码在线中文在线观看| 青青操网| av一区二区三区四区| 国产极品精品美女视频| 中国少妇XXXX做受| 美国aaaaa一级黄片| 亚洲人妻中文高清| 亚洲中文日韩精品| 日韩精品一区二区三区色欲| 综合啪啪| 秋霞 色色| 成人性爱av| 国语精品内射在线观看| 97国产成人精品免费视频| www.色婷婷| 丰满美女一级毛片在线播放| 精品成人无码| 夜夜影视四色| 免费精品福利在线观看| www.yw尤物| heyZO天然素人无码AⅤ专区| 欧美色性爱| 五月婷久久| 超碰97人人cao| 欧美操逼熟女| 色婷婷亚洲婷婷| 欧美大波激情xxxx| 91快色色色色色| 精品综合久久久久久五月天|